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Venous Causes

Who Is at Risk for Venous Ulcers?

Who is at risk for venous ulcers? Learn the medical, lifestyle and skin warning signs, and how a Houston vein specialist lowers risk before a wound opens.

Written by Premier Vein & Vascular Center Clinical TeamReviewed by Premier Vein Blog Review Team
  • Updated Oct 24, 2026
  • 12 min read
Venous CausesUpdated October 24, 202611 min read

Venous ulcers are a serious complication of venous insufficiency. If you have vascular disease, a specialist in Houston may caution you to watch out for open sores on your legs, ankles, or feet that refuse to heal properly. Before these wounds develop, you may notice other signs of venous insufficiency such as itching, swelling, pain, or a feeling of heaviness in the lower extremities. These symptoms warrant a trip to a vein specialist right away because they may mean that you’re at risk of venous ulcers.

Quick Answer: People most at risk for venous ulcers are those with untreated chronic venous insufficiency, especially if they have had a deep vein thrombosis, carry extra weight, stand for long hours, have limited ankle movement, or have already had an ulcer before. Risk climbs with age, multiple pregnancies and a family history of vein disease. The clearest warning is skin change around the ankle, such as brown staining, eczema or hardened skin. At that stage a venous duplex ultrasound and treatment of the faulty veins can often prevent a wound from ever opening.

Other medical conditions may increase your risk of developing venous ulcers include obesity and deep vein thrombosis (DVT). DVT is a potentially dangerous condition in which blood clots develop in the deep veins of the body, typically the legs. Certain lifestyle issues can also place a person at an increased risk of venous ulcers. If you smoke, for instance, your blood circulation is already inhibited even if you haven’t yet been diagnosed with venous insufficiency. Failure to get regular exercise and doing work that requires prolonged periods of standing are other possible risk factors.

Who Is at Risk for Venous Ulcers? The Short List

A venous ulcer is the end point of years of high pressure in the leg veins, so the people at greatest risk are those whose veins have been under strain the longest and whose calf muscles do the least to relieve it. In our practice, the patients who develop ulcers almost always have several risk factors stacked together rather than just one.

The groups we watch most closely are:

  • People with varicose veins or venous insufficiency that has never been evaluated or treated
  • Anyone with a previous deep vein thrombosis, even if it happened many years ago
  • Adults over 60, whose veins and skin have had more time to be damaged
  • People with obesity, particularly when weight is carried around the abdomen
  • Those with stiff ankles, arthritis, paralysis or other conditions that limit walking
  • Anyone who has already had a venous ulcer, because recurrence is common without vein treatment

Most of these factors share the same final pathway: they raise the pressure in the veins at the ankle, which doctors call venous hypertension. The sections below explain how each one does that, and which ones you can change.

How Venous Pressure Damages the Skin

When you walk, the calf muscle squeezes the deep veins and pushes blood up toward the heart. One-way valves stop it falling back between steps. This calf muscle pump is the main reason pressure in the ankle veins drops when you move.

If the valves leak, or the deep veins are scarred or blocked, the pressure at the ankle stays high even while you walk. Over time, that pressure forces fluid and blood cells through the walls of the tiny vessels in the skin. Iron from the red blood cells stains the skin brown. White blood cells trigger ongoing inflammation. The fat beneath the skin gradually scars and hardens. The skin becomes thin and poorly nourished, and eventually a small knock, scratch or patch of dry skin opens into a wound that cannot heal on its own.

This is why risk is really about two things: how high the venous pressure is, and how long it has been going on.

Medical Risk Factors for Venous Ulcers

Untreated venous insufficiency and varicose veins

Reflux in the great or small saphenous vein, the main superficial veins of the leg, is the most common source of ulcer-causing pressure. Many patients have had visible varicose veins for decades and were told they were only cosmetic. Bulging veins combined with ankle swelling and skin changes are not cosmetic; they are a sign that the venous system is under real strain.

Previous deep vein thrombosis

A clot in the deep veins can damage valves as it heals, or leave the vein partly narrowed. The result, called post-thrombotic syndrome, combines reflux and obstruction and produces some of the highest ankle pressures we see. Ulcers related to an old DVT can appear years after the clot, so a history of DVT should always be mentioned to your doctor, even if you were told it resolved.

Obesity

Excess weight in the abdomen raises pressure in the pelvic and leg veins, much like a partial blockage upstream. It also makes walking harder and can weaken the calf pump. Even modest weight loss reduces that pressure and helps compression and vein treatment work better.

Conditions that slow healing

Diabetes, peripheral arterial disease, heart failure, kidney disease, poor nutrition and long-term steroid use do not cause venous ulcers by themselves, but they make a wound more likely to open and much slower to close. Arterial disease matters especially, because it changes how much compression is safe.

Standing or sitting still for long periods

It is not standing itself that does the damage; it is standing still. Nurses, teachers, cashiers, factory and warehouse workers, and hairdressers spend hours upright with little calf movement, so gravity wins. Long periods of sitting, including long drives and desk work, have a similar effect because the calf pump is idle.

Limited ankle movement

The calf pump only works if the ankle bends. Arthritis, old fractures, foot deformity, a shuffling gait or even habitually wearing shoes that restrict the ankle can reduce how much blood each step moves. Patients who walk with a stiff ankle may have high venous pressure even when they are active.

Smoking

Smoking damages the lining of blood vessels, impairs oxygen delivery to tissues and slows every stage of wound healing. For someone with venous disease, quitting is one of the most effective things they can do to protect their skin.

Leg injuries and skin trauma

Many ulcers begin with a minor injury: bumping a shin on a car door, scratching an itchy patch or a small cut while shaving. In healthy skin these heal in days. In skin damaged by venous pressure, they can become chronic wounds. Moisturizing dry skin and treating itching early reduces this trigger.

Comparing Risk Factors: What You Can and Cannot Change

Risk factorHow it raises ulcer riskCan it be changed?What helps
Venous reflux (varicose veins)Keeps ankle vein pressure highYesDuplex ultrasound and vein ablation or sclerotherapy
Previous DVTScarred valves and narrowed deep veinsPartlyCompression, treating superficial reflux, deep vein evaluation
ObesityRaises abdominal and leg vein pressureYesGradual weight loss, regular walking
Prolonged standing or sittingCalf pump idle for hoursYesMovement breaks, compression stockings at work
Stiff ankle or limited mobilityWeak calf muscle pumpPartlyAnkle exercises, physical therapy
SmokingPoor tissue oxygen and healingYesStopping smoking
Age and family historyWeaker vein walls and valvesNoEarlier screening and monitoring

Skin Changes That Signal Rising Risk

Vein specialists grade chronic venous disease from mild to severe using a system called CEAP. The middle stages are the ones that matter most for prevention, because they show the skin is already under stress but has not yet broken down.

  • Swelling of the ankle that is worse in the evening
  • Brown or purple discoloration around the inner ankle
  • Venous eczema, with itching, redness and scaling
  • Lipodermatosclerosis, where the skin above the ankle feels hard and tight and the leg can look like an upside-down bottle
  • Atrophie blanche, small smooth white scars with tiny red dots
  • A healed ulcer scar, which marks the highest risk of all for a new wound

If you recognize any of these on your legs, that is the right time to be evaluated, not after a sore opens. Our vein disease symptoms page explains more of these signs.

How We Evaluate Your Risk for Venous Ulcers

At Premier Vein & Vascular Center, a risk assessment looks at the whole leg, not just the skin.

  1. Focused history. We ask about previous clots, pregnancies, family history, your job and daily activity, smoking, diabetes and any past leg wounds or surgery.
  2. Leg and skin examination. We check for swelling, discoloration, hardened skin, varicose veins, ankle movement and pulses in the feet.
  3. Venous duplex ultrasound. Performed in our IAC-accredited vascular lab, this scan shows which superficial and deep veins are refluxing and whether there is old clot or narrowing.
  4. Arterial check when needed. If pulses are weak or you have diabetes or smoke, an ankle-brachial index confirms that compression is safe.
  5. A clear plan. We explain your findings, your level of risk and the steps that will lower it, from compression and lifestyle changes to vein treatment.

Lowering Your Risk: Prevention and Treatment

Treat the source of the pressure

For patients with superficial vein reflux and skin changes, closing the faulty vein is the most direct way to lower ankle pressure. Options include endovenous thermal ablation, non-thermal ablation and ultrasound-guided foam sclerotherapy. These are office procedures done under local anesthesia, and most patients walk out and return to normal routines within a day or two.

Daily habits that protect your legs

  • Wear prescribed compression stockings during the day, especially at work
  • Walk often, and do ankle pumps every 30 to 60 minutes when sitting or standing still
  • Raise your legs above heart level for 20 to 30 minutes once or twice a day
  • Moisturize the lower legs daily and avoid scratching itchy skin
  • Protect your shins from knocks, and check your ankles for new sores or color changes
  • Stop smoking and work toward a healthy weight

If an ulcer has already formed, the approach shifts to wound healing combined with vein treatment. Our venous ulcer treatment page covers that in detail.

Seek urgent medical care if…

  • One leg suddenly becomes swollen, painful, warm or red, which can signal a deep vein thrombosis
  • You have sudden shortness of breath, chest pain or coughing up blood
  • A leg wound shows spreading redness, increasing pain, pus, a bad odor, or you develop fever or chills
  • A varicose vein bleeds heavily; lie down, raise the leg and press firmly on the spot
  • Your foot turns pale, cold or numb

When to See a Vein Specialist in Houston About Ulcer Risk

If you have varicose veins along with ankle swelling, itching or skin discoloration, a past DVT, or a healed ulcer, it is worth having your veins checked now. Preventing an ulcer takes far less time and effort than healing one.

Dr. Syed Raza is a fellowship-trained interventional radiologist certified by the American Board of Radiology and the Royal College of Radiologists (UK), with more than 15 years of experience treating venous reflux. As a vein clinic in Houston serving Katy and the Greater Houston area, we usually offer same-week appointments and accept most insurance plans, including Medicare. Bring a list of your medications and any previous ultrasound reports to your first visit.

Talk With a Specialist at Premier Vein

Have questions about your symptoms or treatment options? Dr. Syed Raza and the team at Premier Vein & Vascular Center can evaluate your concerns and explain your options clearly. Same-week appointments are usually available, and most insurance plans are accepted.

Frequently Asked Questions

Can you get a venous ulcer without varicose veins?

Yes. Some people have significant reflux or deep vein damage, often after a DVT, without large visible varicose veins. Swelling and skin changes around the ankle can be the only outward signs, which is why a duplex ultrasound is important when those changes appear.

How long after a DVT can a venous ulcer develop?

Ulcers related to post-thrombotic syndrome can appear months or many years after the original clot. Damage to the deep vein valves is permanent, so anyone with a past DVT benefits from long-term attention to compression, skin care and any treatable superficial reflux.

Are venous ulcers more common in women or men?

Varicose veins are more common in women, partly because of pregnancy and hormones, and venous ulcers are seen frequently in older women. Men develop them as well, often after DVT, leg injury or years of standing work, and they may delay seeking care.

Does diabetes cause venous ulcers?

Diabetes does not cause venous ulcers directly, but it slows healing, raises infection risk and often occurs alongside arterial disease. People with diabetes and vein disease need both their veins and arteries checked before compression or treatment is started.

Do compression stockings prevent venous ulcers?

Properly fitted compression stockings reduce swelling and ankle vein pressure and lower the chance of an ulcer forming or returning. They work best when worn every day and combined with treatment of any refluxing veins found on ultrasound.

What is the earliest sign that a venous ulcer may form?

The earliest warnings are usually evening ankle swelling followed by brown discoloration, itching or eczema-like patches around the inner ankle. Skin that feels hard or tight above the ankle is a later sign that the tissue is under significant strain and should be evaluated promptly.

Does pregnancy increase the risk of venous ulcers later in life?

Pregnancy raises blood volume and pressure on the pelvic veins, which can stretch leg vein valves and lead to varicose veins. The risk adds up with each pregnancy. Ulcers are uncommon in young mothers, but untreated reflux that starts during pregnancy can progress over the following decades.

Trusted Health Resources

  1. Chronic Venous Insufficiency, Society for Vascular Surgery
  2. Venous Insufficiency, MedlinePlus Medical Encyclopedia (NIH)
  3. Varicose Veins and Spider Veins, MedlinePlus (NIH)
ABOUT PREMIER VEIN & VASCULAR CENTER:  Premier Vein & Vascular Center, a leading vein clinic in Houston and among the top specialized vein treatment clinics in the USA, has provided expert vein care for over 20 years. The center offers minimally invasive treatments for varicose veins, spider veins, and deep vein thrombosis, led by Dr. Syed Raza, MD, a Board-Certified Vein Specialist and Interventional Radiologist. Dedicated to pain-free, healthier living, the clinic delivers cutting-edge, patient-centered care for optimal results. BLOG DISCLAIMER: The information provided in this blog is for general informational purposes only and should not be considered medical, legal, or professional advice. Always consult a qualified expert for personalized guidance.

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